发明名称 HELICASE-PRIMASE INHIBITORS FOR TREATING ALZHEIMER'S DISEASE
摘要 The present invention relates to the use of helicase-primase inhibitors in a method of treating Alzheimer's Disease (AD). Particularly, the present invention relates to the use of helicase-primase inhibitors in a method of treating AD in a subject that is having HSV-1 infection and is having AD or is having HSV-1 infection and is suspected of having AD. The provided antiviral helicase-primase inhibitors affect the accumulation of the key AD proteins amyloid beta and abnormally phosphorylated tau that occur during HSV-1 infection.
申请公布号 EP2956134(A2) 申请公布日期 2015.12.23
申请号 EP20140703891 申请日期 2014.02.12
申请人 AICURIS GMBH & CO. KG 发明人 ITZHAKI, RUTH
分类号 A61K31/426 主分类号 A61K31/426
代理机构 代理人
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