| 发明名称 |
TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT) |
| 摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s. |
| 申请公布号 |
EP2957636(A2) |
申请公布日期 |
2015.12.23 |
| 申请号 |
EP20150180423 |
申请日期 |
2011.01.13 |
| 申请人 |
CURNA, INC. |
发明人 |
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS;DE LEON, BELINDA |
| 分类号 |
C12N15/63;C07H19/00;C12N15/11;C12Q1/68 |
主分类号 |
C12N15/63 |
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