发明名称 |
COMPOSITION COMPRISING A COMBINATION OF DNA METHYLATION INHIBITOR AND A VITAMIN D RECEPTOR AGONIST FOR THE TREATMENT OF DRUG RESISTANT CANCER OR FOR THE PREVENTION OF TUMOR RELAPSE |
摘要 |
The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer. |
申请公布号 |
WO2015193480(A1) |
申请公布日期 |
2015.12.23 |
申请号 |
WO2015EP63829 |
申请日期 |
2015.06.19 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITÉ PARIS DESCARTES;FONDATION IMAGINE;UNIVERSITÉ PARIS DIDEROT - PARIS 7;UNIVERSITÉ PARIS-SUD;ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) |
发明人 |
CRUZ-MOURA, IVAN;HERMINE, OLIVIER;PAUBELLE, ETIENNE;DUSSIOT, MICHAËL;TROVATI MACIEL, THIAGO;ZYLBERSZTEJN, FLORENCE |
分类号 |
A61K31/593;A61K31/341;A61K31/53 |
主分类号 |
A61K31/593 |
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主权项 |
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地址 |
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