发明名称 COMPOSITION COMPRISING A COMBINATION OF DNA METHYLATION INHIBITOR AND A VITAMIN D RECEPTOR AGONIST FOR THE TREATMENT OF DRUG RESISTANT CANCER OR FOR THE PREVENTION OF TUMOR RELAPSE
摘要 The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer.
申请公布号 WO2015193480(A1) 申请公布日期 2015.12.23
申请号 WO2015EP63829 申请日期 2015.06.19
申请人 INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITÉ PARIS DESCARTES;FONDATION IMAGINE;UNIVERSITÉ PARIS DIDEROT - PARIS 7;UNIVERSITÉ PARIS-SUD;ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) 发明人 CRUZ-MOURA, IVAN;HERMINE, OLIVIER;PAUBELLE, ETIENNE;DUSSIOT, MICHAËL;TROVATI MACIEL, THIAGO;ZYLBERSZTEJN, FLORENCE
分类号 A61K31/593;A61K31/341;A61K31/53 主分类号 A61K31/593
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