发明名称 |
TUBULYSIN COMPOUNDS, METHODS OF MAKING AND USE |
摘要 |
Tubulysin compounds of the formula (I) where R1, R2, R3a, R3b, R4, R5, W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety. |
申请公布号 |
EP2956173(A1) |
申请公布日期 |
2015.12.23 |
申请号 |
EP20140706743 |
申请日期 |
2014.02.10 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CHENG, HENG;CONG, QIANG;GANGWAR, SANJEEV |
分类号 |
A61K47/68;A61P35/00;C07K5/078 |
主分类号 |
A61K47/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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