摘要 |
The present invention provides compounds shown by the formula:
wherein
Y 1 is CR 6 or N,
Y 2 is CR 7 or N,
Y 3 is CR 8 or N,
R 6 , R 7 and R 8 are each independently, a hydrogen atom, halogen, cyano, substituted or unsubstituted alkyl or the like,
Bx is a nucleic acid base moiety,
Z 1 and Z 2 are each independently, a hydrogen atom, a hydroxyl protecting group or a reactive phosphorus group,
R 1 to R 5 are each independently, a hydrogen atom, halogen, cyano, substituted or unsubstituted alkyl or the like, and
n is an integer of 0 to 3,
or salts thereof, that are novel nucleosides or nucleotides that can be useful as materials for synthesizing nucleic acid pharmaceuticals. |