BIOENGINEERED LIVER CONSTRUCTS AND METHODS RELATING THERETO
摘要
An in vitro liver organoid is provided along with methods of making and using the organoid. The liver organoid can be manipulated to have either immature or mature characteristics. Some manipulations generate a liver organoid that supports expansion and/or differentiation of hematopoietic stem cells.
申请公布号
EP2956538(A1)
申请公布日期
2015.12.23
申请号
EP20140706251
申请日期
2014.02.13
申请人
WAKE FOREST UNIVERSITY HEALTH SCIENCES
发明人
ALMEIDA-PORADA, MARIA GRACA;BAPTISTA, PEDRO MIGUEL A.M.;SOKER, SHAY