发明名称 Peptide-based compounds and their uses for tumor imaging and targeting
摘要 The present invention relates to peptide-based compounds comprising (i) at least one peptide comprising the amino acid sequence of TKDNNLLGRFELXG wherein X is S or T and (ii) at least one label and/or drug. The present invention further relates to the use of said peptide-based compounds for tumor imaging and/or tumor targeting. The present invention further relates to the use of said peptide-based compounds as carrier of tumor therapeutic(s). The present invention further relates to methods for the in vitro and/or in vivo visualization, identification and/or detection of tumor cells and/or metastases as well as to methods for the treatment of cancer. The present invention further relates to a screening method for anti-tumor compounds.
申请公布号 EP2957299(A1) 申请公布日期 2015.12.23
申请号 EP20140172984 申请日期 2014.06.18
申请人 KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITÄT MÜNCHEN;HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) 发明人
分类号 A61K47/48;A61K49/00 主分类号 A61K47/48
代理机构 代理人
主权项
地址