摘要 |
There is described a method for making an array of micro-needles, comprising the steps of: depositing a plurality of drops of a liquid substance comprising a polymer on a surface of a starting substrate; positioning a pyroelectric substrate at a certain distance from the starting substrate in such a way that the drops deposited are positioned between said surface of the starting substrate and a surface of the pyroelectric substrate; varying the temperature of the pyroelectric substrate or a part thereof to induce on said surface of the pyroelectric substrate a charge density such that starting from the drops deposited, under the effect of an electrodynamic force, respective cones are formed having a tip facing towards the pyroelectric substrate; determining a consolidation of the cones, to form said micro-needles, preventing the tip of said cones from contacting said surfaces of the pyroelectric substrate. |
申请人 |
CONSIGLIO NAZIONALE DELLE RICERCHE;FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA |
发明人 |
FERRARO, PIETRO;COPPOLA, SARA;FINIZIO, ANDREA;GRILLI, SIMONETTA;VESPINI, VERONICA;NETTI, PAOLO, ANTONIO;VECCHIONE, RAFFAELE;ESPOSITO, ELIANA |