发明名称 |
OIL-IN-WATER EMULSION CONTAINING NO SURFACTANT AND USE THEREOF |
摘要 |
Provided is an oil-in-water emulsion containing no surfactant. The emulsion comprises a metabolizable oil phase, a water phase, and oil-water amphipathic solid particles with biocompatibility dispersed in the water phase, wherein the oil phase comprises squalene or/and tocol; the water phase is any or a combination of at least two of the group consisting of purified water, water for injection, glycerine solutions, buffered saline solutions or clinically transfusable solutions; and the solid particles have an average particle size of nanometer to micron level. The emulsion can be used as a vaccine adjuvant, a medicine deliverer or a slow/controlled release carrier, avoid the use of surfactants and reduce harm to human body and environmental pollution. |
申请公布号 |
WO2015192603(A1) |
申请公布日期 |
2015.12.23 |
申请号 |
WO2014CN92290 |
申请日期 |
2014.11.26 |
申请人 |
INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMYOF SCIENCES |
发明人 |
MA, GUANGHUI;WU, JIE;YANG, LIUQING;XIA, YUFEI;QI, FENG;FAN, QINGZE |
分类号 |
A61K39/39;A61K9/107;A61K47/06;A61K47/14;A61K47/22;A61K47/44;A61P37/02 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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