发明名称 NOVEL TRIIODINATED COMPOUNDS, PREPARATION METHOD THEREOF AND X-RAY CONTRAST COMPRISING THE SAME
摘要 The present invention relates to a novel tri-iodinated compound, a manufacturing method for the novel tri-iodinated compound, and an X-ray contrast agent comprising the same and, more specifically, to a compound represented by Chemical Formula 1, a manufacturing method for the compound, and an X-ray contrast agent comprising the compound. In the present invention, a compound represented by the Chemical Formula 1 shows higher hydrophilicity and maintains lower osmolality than those of the X-ray contrast agent(CT contrast agent) which is currently used, and reduces pain which patients have when injected with the contrast agent. The compound can be used as a new contrast agent through a synthesis with other ligand. In the Chemical Formula 1, the R1 is NH2 or NHCOH.
申请公布号 KR20150143056(A) 申请公布日期 2015.12.23
申请号 KR20140072018 申请日期 2014.06.13
申请人 KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION 发明人 KIM, TAE JEONG;CHANG, YONG MIN
分类号 C07D259/00;A61K49/04;A61K49/10 主分类号 C07D259/00
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