| 主权项 |
1. A method for making 2-substituted-1,4-benzenediamine comprising:
(a) introducing an ether forming agent to a 4-nitro-2- (or 3-) haloalkyl substituted chlorobenzene resulting in the 4-nitro-2 (or 3-) substituted-chlorobenzene: (b) introducing ammonia to a 4-nitro-2- (or 3-)substituted-chlorobenzene to obtain a 4-nitro-
2- (or 3-)substituted-aminobenzene: (c) hydrogenating the 4-nitro-2- (or 3-) substituted-aminobenzene in the presence of an hydrogenation catalyst to form a 2-substituted-1,4-benzenediamine: wherein X1 of formula (IX) is selected from the group consisting of: a C1-C4 alkyl halogen, and mixtures thereof, wherein the halogen is F, Cl or Br; wherein Y of YOH represents an alkyl moiety of C1-C3; wherein the base is selected from suitable alkali alkoxides, alkali hydroxides, and mixtures thereof; and wherein X of formulae (I)-(III)) is selected from the group consisting of:
(a) methoxy, ethoxy, propoxy, isopropoxy, butoxy;(b) C1-C4 alkyl or branched alkyl with hydroxy substitution;(c) —(CH2)yOCH3, wherein y is from 1-3;(d) —(CH2)yOCH2CH3, wherein y is from 1-3;(e) —(CH2)yOCH2CH2CH3, wherein y is from 1-3; and(f) wherein Z is hydrogen, C1-3 alkyl, and mixtures thereof. |
