Anticancer agents of the anthracyclin family

摘要

Anthracyclin compounds of the general structure:;
are disclosed. In these compounds R1 is methyl, acetyl or hydroxyacetyl; R2-R5 and R10-R13 are independently H or methyl; R6 R7 and R8 are independently H, OH or OCH3; and n is zero or one. The compounds are useful for treating cancer.

主权项

1. A compound of formula: wherein R1 is chosen from methyl, acetyl and hydroxyacetyl; R2-R5 and R10-R13 are independently chosen from H and methyl; R6 is chosen from OH and OCH3; R7 and R8 are independently chosen from H, OH and OCH3; and n is zero or one.