Medical device for intra-lumenal delivery of pharmaceutical agents

摘要

The present invention relates to intra-lumenal drug delivery devices. The device, such as a stent, is coated or impregnated with a pharmaceutical agent suitable for use in treatment of restenosis, pulmonary hypertension, and cancer. Suitable pharmaceutical agents include vasodilators and chemotherapeutics.

主权项

1. A device comprising a drug delivery system for implantation in a lumen of a physiologic conduit, an amount of vasoactive intestinal peptide effective to cause vasodilation, and an amount of a chemotherapeutic agent effective to treat a condition responsive to the chemotherapeutic agent proximal to the physiologic conduit and/or distal to the physiologic conduit.