| 发明名称 | GLP-1 receptor agonist compounds having stabilized regions | ||
| 摘要 | The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4. | ||
| 申请公布号 | US9217022(B2) | 申请公布日期 | 2015.12.22 |
| 申请号 | US201113812445 | 申请日期 | 2011.07.27 |
| 申请人 | AstraZeneca Pharmaceuticals LP;Amylin Pharmaceuticals, LLC | 发明人 | Alfaro-Lopez Josue;Sharma Abhinandini;Soares Christopher J.;Coats Eugene;Ghosh Soumitra S. |
| 分类号 | C07K14/605;A61K38/00 | 主分类号 | C07K14/605 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. |
| 主权项 | 1. A compound selected from the group consisting of: | ||
| 地址 | Wilmington DE US | ||