发明名称 métodos e usos envolvendo a proteína de ligação ao heme 1
摘要 The present invention relates to a method of screening for a modulator of endothelial NO synthase (eNOS) expression, a method of diagnosing a cardiovascular disease in a subject, the use of HEBP-1 for the identification of a medicament for preventing and/or treating a disease involving eNOS dysfunction, particularly a cardiovascular disease, the use of HEBP-1 for the detection of a component of eNOS signal transduction, and the use of HEBP1 for the regulation of eNOS promoter activity.
申请公布号 BRPI0922820(A2) 申请公布日期 2015.12.22
申请号 BR2009PI22820 申请日期 2009.11.27
申请人 SANOFI 发明人 ALEXANDRA FERRIER;ALEXANDRA KRUG;CHRISTIAN VISKOV;HARTMUT STROBEL;JOCHEN KRUIP;JOHANN GASSENHUBER;KATHRIN HEERMEIER;NATALIE KARST;PAULUS WOHLFART
分类号 A61K38/00;G01N33/68 主分类号 A61K38/00
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