| 发明名称 |
IgE CH3 peptide vaccine |
| 摘要 |
The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine. |
| 申请公布号 |
US9216229(B2) |
申请公布日期 |
2015.12.22 |
| 申请号 |
US201313904432 |
申请日期 |
2013.05.29 |
| 申请人 |
Pfizer Vaccines LLC |
发明人 |
Brown Alan Daniel;Champion Brian Robert;Lees Clare;Gervais David Paul;Jones Lyn Howard;Kjerrstrom Anne Maria Kristina;Pryde David Cameron;Roberts Lee Richard;Wyatt David Michael |
| 分类号 |
A61K38/04;A61K47/48;A61K39/00;A61K39/395 |
主分类号 |
A61K38/04 |
| 代理机构 |
|
代理人 |
Zhang Austin W. |
| 主权项 |
1. An immunogen comprising at least one antigenic IgE peptide linked to an immunogenic carrier, wherein said antigenic IgE peptide is a functionally active variant of the peptide of SEQ ID NO:220 and consists of an amino acid sequence selected from the group consisting of SEQ ID NOs:221-228, 233, 245, 256, 257, 266, and 267, and wherein the immunogenic carrier is a Qbeta VLP. |
| 地址 |
New York NY US |
