Esophageal mucosectomy systems, devices and methods

摘要

Systems, devices, apparatus and methods that may be used for en bloc circumferential esophageal mucosal resection or ablation that can extend over only a selected portion or all of the length of the esophagus.

主权项

1. An esophageal mucosectomy system comprising:
a dissection device configured to dissect mucosal tissue in circumferential direction at a selected location within an esophagus, wherein the dissected mucosal tissue forms a free end of mucosal tissue separated from submucosal tissue;
a mucosectomy device comprising:
a body having a proximal end and distal end, wherein a longitudinal axis extends between the proximal end and the distal end,a cauterizing ring located at the distal end of the body, the cauterizing ring capable of separating mucosal tissue from submucosal tissue about the entire circumference of the esophagus as the distal end of the mucosectomy device is advanced therethrough,an expandable support structure supporting the cauterizing ring, wherein the support structure is expandable from a delivery configuration to a deployed configuration, wherein the diameter of the cauterizing ring is larger in the deployed configuration than in the delivery configuration, and further wherein the body of the mucosectomy device is narrower at the proximal end than at the support structure when the support structure is in the deployed configuration, and further wherein the cauterizing ring defines an opening when the support structure is in the deployed configuration, wherein the longitudinal axis extends through the opening when the support structure is in the deployed configuration; and a mucosal tissue retention apparatus comprising one or more connectors configured to retain the free end of mucosal tissue and one or more elongate elements attached to the one or more connectors, wherein the one or more elongate elements extend along the longitudinal axis through the opening defined by the cauterizing ring when the support structure is in the deployed configuration.