| 发明名称 |
TREATMENT OF SIRTUIN 1 (SIRT1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRT1 |
| 摘要 |
PROBLEM TO BE SOLVED: To provide oligonucleotide compounds that modulate the expression of and/or function of Sirtuin 1 (SIRT1) polynucleotides and encoded products thereof.SOLUTION: The present invention provides methods for treating diseases associated with Sirtuin 1 (SIRT1), comprising the step of administering to patients one or plural oligonucleotide compounds designed to inhibit SIRT1 natural antisense transcripts. |
| 申请公布号 |
JP2015228868(A) |
申请公布日期 |
2015.12.21 |
| 申请号 |
JP20150167752 |
申请日期 |
2015.08.27 |
| 申请人 |
CURNA INC |
发明人 |
JOSEPH COLLARD;OLGA KHORKOVA SHERMAN;CARLOS COITO;BELINDA DE LEON |
| 分类号 |
C12N15/113;A61K31/7088;A61K31/7115;A61K31/7125;A61K48/00;A61P1/04;A61P1/16;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P19/02;A61P19/08;A61P19/10;A61P21/04;A61P25/00;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P27/12;A61P29/00;A61P35/00;A61P35/02 |
主分类号 |
C12N15/113 |
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