发明名称 |
Fremgangsmåde til diagnose, prognose og behandling af brystcancermetastase |
摘要 |
<p>The present invention relates to a method for the diagnosis or the prognosis of metastasis in breast cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in ER- breast cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the ER- breast cancer metastasis.</p> |
申请公布号 |
DK2626431(T3) |
申请公布日期 |
2015.12.21 |
申请号 |
DK20110791605T |
申请日期 |
2011.10.05 |
申请人 |
FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA);FUNDACIÓ PRIVADA INSTITUCIÓ CATALANA DE RECERCA IESTUDIS AVANÇATS |
发明人 |
GOMIS CABRÉ, ROGER;TARRAGONA SUNYER, MARÍA;ARNAL ESTAPÉ, ANNA;PAVLOVIC, MILICA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|