发明名称 METHOD FOR ASSESSING LEVEL OF UNFRACTIONATED HEPARIN INDUCED ANTICOAGULATION IN HAEMODIALYSIS IN PATIENTS WITH ACUTE RENAL INJURY
摘要 FIELD: medicine.SUBSTANCE: performing a haemodialysis procedure in the periods of time: prior to administration of unfractionated heparin, then 10, 30, 60 minutes after a bolus, then 10 minutes after another bolus, and 5 minutes before the haemodialysis procedure is completed, is accompanied by performing a low-frequency piezothromboelastography and measuring blood viscosity parameters, as follows: t1 is the A1 achievement time (min); t2 is the time of an amplitude A increase by 100 units (min); TAC is a thrombin activity constant defined as the time from the end of a reaction period to the amplitude A increase by 100 units from the minimum amplitude for the reaction period (relative units), and calculated by formula: TAC = 100/(t2-t1). If TAC after the UFH bolus administration is 2-3 times less than the reference, the anticoagulation level is considered optimum.EFFECT: using the invention enables providing more effective heparinisation control and reducing the investigation time.1 tbl, 2 dwg, 1 ex
申请公布号 RU2571505(C1) 申请公布日期 2015.12.20
申请号 RU20140153815 申请日期 2014.12.29
申请人 OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOST'JU "MED-NORD" (OOO "MED-NORD") 发明人 TJUTRIN IVAN ILLARIONOVICH;UDUT VLADIMIR VASIL'EVICH;MALJUGIN EVGENIJ FEDOROVICH;KLIMENKOVA VALENTINA FEDOROVNA
分类号 G01N33/48 主分类号 G01N33/48
代理机构 代理人
主权项
地址