| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medicine, namely gastroenterology, and aims at predicting the routine antiretroviral therapy outcomes in chronic hepatitis B. That is ensured by measuring patient's blood serum ?-interferon and induced ?-interferon. An ultrasonic scanning of the spleen aims at measuring its section. A discriminator function is calculated by formula: DF = 5.3769x-0.8186x-0.4369x, wherein DF is the discriminator function; xis the spleen section, mm; xis the serum ?-interferon concentration, IU/ml; xis the induced ?-interferon concentration, IU/ml. The values 5.3769; - 0.8186; and - 0.4369 are discriminator function coefficients. The derived discriminator function is compared to a constant which is 296.1005. If the discriminator function is more than 296.1005, a recurrence is predicted, whereas the discriminator function of 296.1005 or less makes it possible to predict a stable response to the routine antiretroviral therapy of chronic hepatitis B.EFFECT: using the presented method enables predicting the outcomes before the routine antiretroviral therapy of chronic hepatitis B starts by means of the ultrasonic scanning of the spleen and the blood ?-interferon concentration measurement.2 ex |
