发明名称 CHIMERIC ADENOVIRUSES FOR USE IN CANCER TREATMENT
摘要 The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
申请公布号 HK1205529(A1) 申请公布日期 2015.12.18
申请号 HK20150106084 申请日期 2015.06.26
申请人 PSIOXUS THERAPEUTICS LTD. 发明人 HARDEN, PAUL;HERMISTON, TERRY;KUHN, IRENE
分类号 C12N;A61K35/76;A61K48/00;A61P;C12N7/00;C12N7/01;C12N7/02;C12N15/861;C12R 主分类号 C12N
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