| 摘要 |
PROBLEM TO BE SOLVED: To provide a production method of 2,3-dihalogenoaniline in a high yield without high-temperature, high-pressure reaction conditions.SOLUTION: A production method of 2,3-dihalogenoaniline includes a step of substituting the 3-halogeno group of a 1,2,3-trihalogeno-4-nitrobenzene with an amino group to obtain 2,3-dihalogeno-6-nitroaniline, making succinic acid to act on the amino group so as to obtain 1-(2,3-dihalogeno-6-nitrophenyl)pyrrolidin-2,5-dione, reducing the 6-nitro group of the obtained 1-(2,3-dihalogeno-6-nitrophenyl)pyrrolidin-2,5-dione to convert into 6-amino group so as to obtain 1-(2,3-dihalogeno-6-aminophenyl)pyrrolidin-2,5-dione (formula (IV)) and reducing the 6-amino group to cleave 2,5-dioxo-1-pyrrolidinyl group so as to induce to an amino group. |
