TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE
摘要
The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
申请公布号
CA2950305(A1)
申请公布日期
2015.12.17
申请号
CA20152950305
申请日期
2015.06.11
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
SESSLER, JONATHAN L.;ARAMBULA, JONATHAN;SIDDIK, ZAHID H.;THIABAUD, GREGORY