发明名称 |
INTELLIGENT TARGET-BASED ACQUISITION |
摘要 |
A method of mass spectrometry comprises ionising a sample eluting from a separation device in order to generate a plurality of parent ions. The method further comprises generating a target list of ions, which includes a predicted mass to charge ratio, a predicted chromatographic retention or elution time, and a predicted ion mobility drift time, derived from a model. Multiple cycles of operation are then performed as the sample elutes from the separation device. Each cycle of operation includes mass filtering the parent ions so that selected ions having mass to charge ratios within a first mass to charge ratio range are onwardly transmitted to a fragmentation or reaction device. The target list is then checked and the model is updated accordingly. The first mass to charge ratio range can then be adjusted in response to the updated model. |
申请公布号 |
WO2015191980(A1) |
申请公布日期 |
2015.12.17 |
申请号 |
WO2015US35521 |
申请日期 |
2015.06.12 |
申请人 |
WATERS TECHNOLOGIES CORPORATION |
发明人 |
GEROMANOS, SCOTT, J.;CIAVARINI, STEVEN, J.;CHEN, WEIBIN;HOUEL, STEPHANE |
分类号 |
H01J49/10;G01N30/72;H01J49/14 |
主分类号 |
H01J49/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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