CLOSED DRUG TRANSFER SYSTEM

摘要

The application describes innovative designs for components of a drug transfer apparatus that overcome problems encountered in daily use of prior art apparatuses. Specifically described are components configured to prevent liquid from entering the air chamber of syringes coupled to the apparatus and to prevent tearing of the rubber stopper of drug vials when they are attached to the apparatus.

主权项

1. A fluid transfer apparatus comprising:
(a) a syringe-like proximal section comprising:
(i) a cylindrical body;(ii) a piston that is displaceable within said cylindrical body, said piston defining a distal liquid chamber and a proximal air chamber, both of variable volume; (b) a connector section fixedly attached to the distal end of said proximal section, wherein the distal end of said connector section is adapted to be connectable to a fluid transfer component, said connector section comprising:
(i) a needle holder;(ii) a liquid conduit that passes through and is rigidly attached to said needle holder, wherein the distal end of said liquid conduit begins in said connector section and the proximal end of said liquid conduit terminates in said distal liquid chamber;(iii) an air conduit that passes through and is rigidly attached to said needle holder, wherein the distal end of said air conduit begins in said connector section and the proximal end of said air conduit terminates in said proximal air chamber; and(iv) a membrane located at the distal end of said connector section, wherein said membrane encloses the distal ends of said liquid conduit and said air conduit isolating them from the surroundings; wherein, said connector section is configured to allow a head portion of said fluid transfer component to enter the interior of said connector section and to allow said membrane in said connector section to be pushed proximally when it is contacted by a membrane located in said head portion of said fluid transfer component; whereupon further pushing of said membranes together causes said distal ends of said liquid conduit and said air conduit to penetrate said membrane in said connector section and to penetrate said membrane in said head portion, thereby establishing a liquid channel via said liquid conduit between the interior of said distal liquid chamber and the interior of said fluid transfer component and a separate air channel via said air conduit between the interior of said proximal air chamber and the interior of said fluid transfer component; said fluid transfer apparatus characterized in that a hydrophobic filter is inserted in said air channel in at least one location between said proximal air chamber in said syringe-like proximal section of said fluid transfer apparatus and said fluid transfer component.