| 摘要 |
Disclosed in the present invention is a method for screening cancer, comprising the following steps: (1) providing a specimen to be detected; (2) detecting the methylation status of CpG sequence of at least one target gene which is at least one of ADRA1D, AJAP1, HS3ST2, MAGI2, POU4F2, POU4F3, PTGDR, SOX17 and SYT9 in genomic DNA of the specimen; (3) determining whether cancer or precancerous lesions are present in the specimen according to the methylation status of at least one target gene. |
| 主权项 |
1. A method III for screening cancer, which detects the methylation status of target gene in the cells of a specimen to be detected, and the detection serves as a screening indicator of the presence or absence of cancer, characterized in that the method comprises the following steps:
step 1: providing the specimen to be detected; step 2: detecting the methylation status of CpG sequence of at least one target gene which is at least one of ADRA1D, AJAP1, HS3ST2, MAGI2, POU4F2, POU4F3, PTGDR, SOX17 and SYT9 in genomic DNA of the specimen; and step 3: determining whether cancer or precancerous lesions are present in the specimen according to the methylation status of the target gene, or utilizing the methylation status as an indicator of prognosis after treatment. |
