发明名称 COMPOSITION OF ANTI-ENDO180 ANTIBODIES AND METHODS OF USE FOR THE TREATMENT OF CANCER AND FIBROTIC DISEASES
摘要 The present invention provides antibodies or antigen-binding fragments thereof that specifically bind the ENDO180 polypeptide and are internalized thereby, to conjugates comprising the molecules, to compositions comprising the antibodies and conjugates and to methods of using the same for delivery of therapeutic agents to cells that express the ENDO180 polypeptide on the surface of the cell for treating cell proliferative diseases or disorders and fibrosis, and for controlling (modulating) tumor progression.
申请公布号 US2015359905(A1) 申请公布日期 2015.12.17
申请号 US201514795429 申请日期 2015.07.09
申请人 Feinstein Elena 发明人 Feinstein Elena
分类号 A61K47/48;A61K49/00;C07K16/28 主分类号 A61K47/48
代理机构 代理人
主权项
地址 Rehovot IL