PROCESS AND INTERMEDIATES FOR PREPARING POLY(ANHYDRIDE-ESTERS)
摘要
Certain embodiments of the invention provide a method comprising treating a hydroxy-carboxylic acid compound with a compound of formula (I) in the absence of a solvent, to provide a diacid of formula (II), wherein R is a linker molecule; wherein each Y is independently a leaving group; and wherein X is a residue of a biologically active compound.
申请公布号
WO2015191742(A1)
申请公布日期
2015.12.17
申请号
WO2015US35143
申请日期
2015.06.10
申请人
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;UHRICH, KATHRYN E.;FAIG, JONATHAN J.;SMITH, KERVIN
发明人
UHRICH, KATHRYN E.;FAIG, JONATHAN J.;SMITH, KERVIN