发明名称 |
COMBINATION THERAPY COMPRISING A LIPOSOMAL PRODRUG OF MITOMYCIN C AND RADIOTHERAPY |
摘要 |
A method of treating neoplasia in a subject in need of treatment is provided by administering to the subject an amount of a prodrug of mitomycin C that yields a therapeutically effective amount of mitomycin C, in combination with radiation therapy. In one embodiment, the prodrug of mitomycin C is a liposomal-prodrug of mitomycin C. Together, the prodrug of mitomycin C and radiation therapy provide a synergistic antineoplastic effect. |
申请公布号 |
WO2015191576(A1) |
申请公布日期 |
2015.12.17 |
申请号 |
WO2015US34897 |
申请日期 |
2015.06.09 |
申请人 |
LIPOMEDIX PHARMACEUTICALS LTD.;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
GABIZON, ALBERTO;OHANA, PATRICIA;WANG, ANDREW |
分类号 |
A61K47/48;A61K9/127;A61P35/00 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|