| 摘要 |
Implants for vertebral body or functional spinal unit replacement comprise a bioactive surface roughening on one or more of the anterior, posterior, and lateral surfaces of the implant. The bioactive surface includes macro-, micro-, and nano-scale structural features that contact vertebral bone that lines a specialized channel in a vertebrae, and thereby facilitate bone growth and osteointegration of the implant with the vertebral bone. |
| 主权项 |
1. An implant, comprising:
a body that is generally oval-shaped in transverse cross section, has a height substantially the same as the height of a functional spinal unit, and comprises: a top surface, a bottom surface, opposing lateral sides, opposing anterior and posterior sides, a substantially hollow center, and a single vertical aperture, extending from the top surface to the bottom surface, having maximum width at its center, and defining a transverse rim on the top surface and on the bottom surface, said transverse rim having a posterior thickness greater than an anterior thickness, and having a blunt and radiused portion along the top of each lateral side and the top of the posterior portion, wherein the portion of the transverse rim that is not blunt and radiused, the posterior side, and at least a portion of each opposing lateral side each have a bioactive roughened surface, wherein the blunt and radiused portion does not include any bioactive roughened surface, and wherein the body has a sharp edge at the junction of the anterior side and the top surface and at the junction of the anterior side and the bottom surface. |
