| 发明名称 |
LIPIDS, LIPID COMPLEXES AND USE THEREOF |
| 摘要 |
The present invention is related to uses of a composition comprising a pharmaceutically active component and a compound according to formula (I),;wherein R1 and R2 are each and independently selected from the group comprising alkyl;n is any integer between 1 and 4;R3 is an acyl selected from the group comprising lysyl, ornithyl, 2,4-diaminobutyryl, histidyl and an acyl moiety according to formula (II),;wherein m is any integer from 1 to 3 andY− is a pharmaceutically acceptable anion. |
| 申请公布号 |
US2015359906(A1) |
申请公布日期 |
2015.12.17 |
| 申请号 |
US201514838791 |
申请日期 |
2015.08.28 |
| 申请人 |
SILENCE THERAPEUTICS GMBH |
发明人 |
KEIL OLIVER;KAUFMANN JÖRG;SANTEL ANSGAR |
| 分类号 |
A61K47/48;A61K47/24;A61K47/18;A61K9/127;C12N15/113 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a carrier and a liposome comprising at least one helper lipid component selected from the group consisting of phospholipids and steroids and a compound according to formula (I), wherein R1 and R2 are each and independently selected from the group comprising alkyl; n is any integer between 1 and 4; R3 is an acyl selected from the group comprising lysyl, ornithyl, 2,4-diaminobutyryl, histidyl and an acyl moiety according to formula (II) wherein m is any integer from 1 to 3 and Y− is a pharmaceutically acceptable anion. |
| 地址 |
BERLIN DE |
