| 发明名称 |
DEVELOPMENT OF STABLE COLD-ADAPTED TEMPERATURE SENSITIVE CHIMERIC ENTEROVIRUSES |
| 摘要 |
The present invention relates to chimeric virus strains, particularly to the stable cold- adapted temperature sensitive Enterovirus 71 strains EV71 :eTLLβP20 and EV71 :TLLeC5 and to the stable chimeric enterovirus strain TLLeCA16. The present invention also relates to vectors containing the nucleotide sequences of these strains and vaccines containing these strains. |
| 申请公布号 |
WO2015190999(A1) |
申请公布日期 |
2015.12.17 |
| 申请号 |
WO2015SG50106 |
申请日期 |
2015.05.12 |
| 申请人 |
TEMASEK LIFE SCIENCES LABORATORY LIMITED |
发明人 |
CHUA, KAW BING |
| 分类号 |
C12N7/04;A61K39/125;A61K39/135;C12N7/01;C12N15/41;C12N15/42 |
主分类号 |
C12N7/04 |
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