发明名称 |
COMPOUNDS COMPRISING 1,1',2,5'-TETRAHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,5'-DIONE SYSTEM AS INHIBITORS P53-MDM2 PROTEIN-PROTEIN INTERACTION |
摘要 |
A spirooxoindole compound represented by the formula selected from the group consisting of Formula (IA) and (IB), wherein all symbols are as defined in the description. The compound can find use in a method of prevention and/or treatment of diseases selected from the group consisting of cancer, immune diseases, inflammatory conditions, allergic skin diseases associated with excessive proliferation, and viral infections. |
申请公布号 |
CA2947134(A1) |
申请公布日期 |
2015.12.17 |
申请号 |
CA20152947134 |
申请日期 |
2015.06.11 |
申请人 |
ADAMED SP. Z O.O. |
发明人 |
FEDER, MARCIN;KALINOWSKA, IWONA;JASZCZEWSKA, JOANNA ADRIANA;BURCHARD, EWA;LEWANDOWSKI, WOJCIECH;BULKOWSKA, URSZULA;MAZUR, MARIA;WOS, KATARZYNA |
分类号 |
C07D487/10;A61K31/407;A61K31/4162;C07D487/20 |
主分类号 |
C07D487/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|