| 发明名称 |
(N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOPHENYLAMINO)PYRIMIDIN-4-YL)BENZAMIDE |
| 摘要 |
The present invention relates to stable novel salt forms of N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide that are suitable for the preparation of pharmaceutical formulations thereof, and their therapeutic use. |
| 申请公布号 |
US2015361050(A1) |
申请公布日期 |
2015.12.17 |
| 申请号 |
US201514736690 |
申请日期 |
2015.06.11 |
| 申请人 |
Gilead Sciences, Inc. |
发明人 |
Brown Brandon H.;Carra Ernest A.;Hemenway Jeffrey N.;Morrison Henry;Reynolds Troy;Shi Bing;Stefanidis Dimitrios;Wang Fang;Warr Matthew Robert;Whitney James Andrew;Xin Yan |
| 分类号 |
C07D239/42 |
主分类号 |
C07D239/42 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A compound selected from the group consisting of:
N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide dihydrochloride monohydrate Form II; N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide monohydrochloride anhydrous Form I; and N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide monohydrochloride anhydrous Form III. |
| 地址 |
Foster City CA US |
