摘要 |
PROBLEM TO BE SOLVED: To provide methods and reagents for signal amplification.SOLUTION: The present invention provides reagents containing binding moieties conjugated to dextran moieties, methods of making such reagents, and use of such reagents in a variety of molecular and cellular assays. The present invention is based at least in part on the discovery that a plurality of dextrans and their configuration can be used as part of detectable reagents. Accordingly the present invention provides detectable reagents containing a plurality of dextrans useful for various detection assays, e.g., cell detection assays. In some embodiments, the present invention provides detectable reagents containing a binding moiety conjugated to a dextran component. The dextran component can be further bonded to a detectable entity. |