| 发明名称 |
OVARIAN CANCER VACCINES AND VACCINATION METHODS |
| 摘要 |
Compositions of multipeptide vaccines including tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from tumor associated antigens, and methods of making same, are provided herein. Also, disclosed are methods for treating ovarian cancers using such vaccines. |
| 申请公布号 |
US2015359867(A1) |
申请公布日期 |
2015.12.17 |
| 申请号 |
US201414766711 |
申请日期 |
2014.02.14 |
| 申请人 |
IMMUNOCELLULAR THERAPEUTICS, LTD. ;CEDARS-SINAI MEDICAL CENTER |
发明人 |
Yu John S.;Li Zhenhua;Orsulic Sandra;Karlan Beth Y.;Bender James G. |
| 分类号 |
A61K39/00;A61K31/675;C12N5/0784;A61K45/06 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising a pharmaceutically acceptable carrier, an adjuvant, and a mixture of at least one major histocompatibility complex (MHC) class I epitope of at least five antigens selected from the group consisting of mesothelin, HER-2/neu, IL-13 receptor α2, survivin, CD133, gp100, AIM-2, and epidermal growth factor receptor (EGFR). |
| 地址 |
Calabasas CA US |
