发明名称 KRAS遺伝子変異型の結腸直腸癌患者に対する抗腫瘍剤及び治療効果予測方法
摘要 This invention provides a method for predicting a therapeutic effect of chemotherapy that uses an antitumor agent comprising ±,±,±-trifluorothymidine and 5-chloro-6-(1-(2-iminopyrrolidinyl)methyl)uracil hydrochloride at a molar ratio of 1:0.5 on a colorectal cancer patient, the method comprising: (1) detecting the presence or absence of KRAS gene mutation in a biological sample obtained from the patient; and (2) predicting that the patient is likely to sufficiently respond to the chemotherapy, when KRAS gene mutation is detected in Step (1).
申请公布号 JP5832541(B2) 申请公布日期 2015.12.16
申请号 JP20130529023 申请日期 2012.08.15
申请人 大鵬薬品工業株式会社 发明人 伊藤 雅信;岡部 博之
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
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