Methods and apparatus for facilitating monitoring in a clinical trial. The method includes acts of receiving data from at least one information technology system configured to process clinical trial data, and assigning a site prioritization to each of a plurality of sites for at least one clinical trial associated with the at least one information technology system. Assigning a site prioritization is based, at least in part, on the received data. The method further includes an act of outputting an indication of the site prioritization.