| 发明名称 |
Promiscuous HER-2/NEU CD4 T cell epitopes |
| 摘要 |
<p>The present invention relates to the discovery of novel T cell epitopes of the human HER-2/Neu protein that is promiscuous for at least 25 different HLA-DR alleles. The invention also relates to compositions that contain one of the novel epitopes or a fusion peptide of such a epitope and a heterologous polypeptide. Further disclosed herein is the use of the epitopes or their fusion peptides, and compositions containing the epitopes or their fusion peptides.</p> |
| 申请公布号 |
EP2570422(B1) |
申请公布日期 |
2015.12.16 |
| 申请号 |
EP20120168585 |
申请日期 |
2007.08.10 |
| 申请人 |
DENDREON CORPORATION |
发明人 |
WOLLAN, JAMI B.;JONES, LORI A. |
| 分类号 |
C07K14/00;A61K38/00;C07H21/00;C12Q1/00;G01N33/53 |
主分类号 |
C07K14/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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