| 发明名称 |
PDES AS MODIFIERS OF THE IGFR PATHWAYS AND METHODS OF USE |
| 摘要 |
Human PDE genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of PDE are provided
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| 申请公布号 |
US2009013416(A1) |
申请公布日期 |
2009.01.08 |
| 申请号 |
US20050592605 |
申请日期 |
2005.03.10 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
FRIEDMAN LORI;FRANCIS-LANG HELEN;PARKS ANNETTE L.;SHAW KENNETH JAMES;BJERKE LYNN MARGARET;HEUER TIMOTHY S. |
| 分类号 |
A61K49/00;A61K38/00;C07K1/00;C12N5/00;C12N15/00;C12Q1/02;C12Q1/44;C12Q1/68;G01N33/50;G01N33/53;G01N33/536;G01N33/566;G01N33/574;G01N33/74 |
主分类号 |
A61K49/00 |
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