发明名称 PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS 1,2,3,4,4A,10A-HEXAHIDRO (10 H) 1-BENZOPIRANO-(3,2-C)-PIRIDINAS.
摘要 <p>1,178,360. Antiphlogistic &c. compositions. KARL THOMAE G.m.b.H. 21 June, 1968 [21 June, 1967], No. 29789/68. Heading A5B. [Also in Division C2] Pharmaceutical compositions having antiphlogistic and sedative properties comprise, as active ingredient, at least -one 1,2,3,4,4a,10ahexahydro-(10H)-1-benzopyrano [3,2-C]. pyridine of the general formula wherein R 1 is a straight- or branched-chain C 1-4 alkenyl or alkynyl group or a cyclopropyl- C 1-4 alkyl or a -C 1-4 alkyl group; R 2 and R 3 are each a hydrogen or halogen atom or a C 1-4 alkyl or alkoxy group; and R 4 is a hydrogen atom or a C 1-4 alkyl group; and/or a physiologically acceptable acid addition salt thereof, together with a pharmaceutical carrier or excipient. An example is also given of a composition of the above type with pyramidone as an additional ingredient. The compositions may be administered orally in the form of granules, tablets, coated tablets, capsules, syrups, emulsions, suspensions or drops; parenterally in the form of sterile, parenterally acceptable liquids contained in ampoules; and rectally in the form of suppositories. Conventional carriers and excipients are used.</p>
申请公布号 ES355231(A1) 申请公布日期 1969.11.16
申请号 ES19310003552 申请日期 1968.06.20
申请人 DR. KARL THOMAE G. M. B. H. 发明人
分类号 A61K31/00;C07D491/04;C07D491/052;(IPC1-7):07D/ 主分类号 A61K31/00
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