| 发明名称 |
TET REPRESSOR-BASED TRANSCRIPTIONAL REGULATORY PROTEINS |
| 摘要 |
<p>The present invention provides a panel of transcriptional activator fusion proteins which comprises both tetracycline controlled transactivator proteins and reverse tetracycline transactivator proteins. These transactivators have novel phenotypes such as altered basal transcriptional activity in the absence of doxycycline, altered induced transcriptional activity in the presence of doxycycline, or differential induction by tetracycline and analogs of tetracycline.</p> |
| 申请公布号 |
EP1200607(B1) |
申请公布日期 |
2010.02.24 |
| 申请号 |
EP20000938973 |
申请日期 |
2000.06.05 |
| 申请人 |
TET SYSTEMS HOLDING GMBH & CO. KG |
发明人 |
HILLEN, WOLFGANG;BUJARD, HERMANN;URLINGER, STEFANIE |
| 分类号 |
A01K67/027;C12N15/62;A61K31/65;A61K35/74;A61K35/76;A61K48/00;A61P31/12;A61P35/00;C07K14/16;C07K14/47;C07K19/00;C12N1/19;C12N5/10;C12N15/00;C12N15/09;C12N15/63;C12N15/85;C12P21/02 |
主分类号 |
A01K67/027 |
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