发明名称 COPOLYMERS OF N-VINYL AMIDES WITH UNSATURATED SORBOSE ESTERS
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to the chemistry of high-molecular compounds, specifically to copolymers of N-vinyl amides. According to the invention, the copolymer is characterised by general formula An-Bm, where A is an N-vinyl amide residue, B is a vinyl saccharide residue, and where n=100-m mol %; m=10.0-35.0 mol %. The vinyl saccharide residue used is (meth)acryloyl-sorbose, crotonoyl-sorbose. The N-vinyl amide residues used are N-vinyl formamide, N-vinyl pyrrolidone, N-methylvinyl amide. The copolymers are obtained in the presence of a radical initiator - dinitrile of azo-isobutyric acid, and then hydrolysed in aqueous solution of formic acid. ^ EFFECT: water-soluble copolymers in accordance with the invention have low-toxicity and high level of immuno-stimulating activity. ^ 1 cl, 10 ex, 2 tbl
申请公布号 RU2381239(C1) 申请公布日期 2010.02.10
申请号 RU20080128345 申请日期 2008.07.11
申请人 INSTITUT VYSOKOMOLEKULJARNYKH SOEDINENIJ ROSSIJSKOJ AKADEMII NAUK 发明人 PANARIN EVGENIJ FEDOROVICH;IVANOVA NADEZHDA PETROVNA;ZHURAVSKAJA OL'GA NIKOLAEVNA;NESTEROVA NATAL'JA ALEKSANDROVNA;BELOKHVOSTOVA ALEKSANDRA TIMOFEEVNA;POTAPENKOVA LJUBOV' SERGEEVNA
分类号 A61K31/79;A61P37/04;C08F226/06;C08F226/10 主分类号 A61K31/79
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