| 发明名称 |
NOVEL MHC CLASS II RESTRICTED T CELL EPITOPES FROM THE CANCER ANITGEN, NY ESO-1 |
| 摘要 |
The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4+ T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
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| 申请公布号 |
US2010021468(A1) |
申请公布日期 |
2010.01.28 |
| 申请号 |
US20090568134 |
申请日期 |
2009.09.28 |
| 申请人 |
THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPART. OF HEALTH AND HUMAN SERVICE |
发明人 |
WANG RONG-FU;ROSENBERG STEVEN A.;ZENG GANG |
| 分类号 |
A61K39/395;C12N15/09;A01K67/027;A61K31/7088;A61K35/12;A61K35/14;A61K35/76;A61K38/00;A61K38/17;A61K39/00;A61K39/39;A61K45/00;A61K48/00;A61P35/00;C07H21/04;C07K7/06;C07K7/08;C07K14/47;C07K14/705;C07K14/82;C07K16/28;C07K16/30;C07K16/32;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/0783;C12N5/10;C12N7/00;C12N7/01;C12N15/12;C12N15/63;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;C12R1/91;G01N33/53 |
主分类号 |
A61K39/395 |
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