摘要 |
The present invention discloses novel compounds of Formula I: (I) having 11-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11-HSD type 1 activity. |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
BUSH, JULIE KAY;HANSEN, MARVIN MARTIN;LI, RENHUA;MABRY, THOMAS EDWARD;SNYDER, NANCY JUNE;WALLACE, OWEN BRENDAN;XU, YANPING |