| 发明名称 |
A METHOD FOR THE PREPARATION OF 18F-LABELLED FOLATES |
| 摘要 |
<p>The present invention is directed towards a new method of synthesis of 18F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18[F]fluoride, as well as 18F-folate radiopharmaceuticals obtained by such method of synthesis and their use in diagnosis and monitoring of cancer therapy and therapy of inflammatory and autoimmune diseases.</p> |
| 申请公布号 |
EP2146944(A1) |
申请公布日期 |
2010.01.27 |
| 申请号 |
EP20080736117 |
申请日期 |
2008.04.11 |
| 申请人 |
MERCK EPROVA AG |
发明人 |
AMETAMEY, SIMON MENSAH;MOSER, RUDOLF;ROSS, TOBIAS LUDWIG;LAM, PHOEBE;GROEHN, VIOLA |
| 分类号 |
C07D475/04;A61B5/00;A61K51/04;C07B59/00 |
主分类号 |
C07D475/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
