发明名称 LXR AND FXR MODULATORS
摘要 <p>Compounds of the invention are disclosed, such as compounds of formulae LX-LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.</p>
申请公布号 EP2121621(A1) 申请公布日期 2009.11.25
申请号 EP20070865385 申请日期 2007.12.07
申请人 EXELIXIS, INC. 发明人 BOREN, BRANT CLAYTON;BUSCH, BRETT B.;GU, XIAO-HUI;JAMMALAMADAKA, VASU;LU, SHAO-PO;MARTIN, RICHARD;MOHAN, RAJU;SCHWEIGER, EDWIN;STEVENS, WILLIAM C. JR.;WANG, TIE-LIN;XIE, YINONG;XU, WEI
分类号 C07D233/90;A61K31/415;A61K31/4164;A61P3/10;C07D231/10 主分类号 C07D233/90
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