摘要 |
<p>Compounds of the invention are disclosed, such as compounds of formulae LX-LXIV, and pharmaceutically acceptable salts, isomers, or prodrugs thereof, which are useful as modulators of the activity of liver X receptors (LXR) and Farnesoid X receptors (FXR), where R00, R200, R400, R500, J11, J21, G1, G21, and Q are defined herein. Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed.</p> |
申请人 |
EXELIXIS, INC. |
发明人 |
BOREN, BRANT CLAYTON;BUSCH, BRETT B.;GU, XIAO-HUI;JAMMALAMADAKA, VASU;LU, SHAO-PO;MARTIN, RICHARD;MOHAN, RAJU;SCHWEIGER, EDWIN;STEVENS, WILLIAM C. JR.;WANG, TIE-LIN;XIE, YINONG;XU, WEI |