Aminophenylsulfonamide derivatives as HIV protease inhibitor
摘要
The present invention concerns substituted aminophenylsulfonamide compounds and derivatives, their use as protease inhibitors, in particular as broadspectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds and derivatives with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents.
申请公布号
ZA200804610(B)
申请公布日期
2009.11.25
申请号
ZA20080004610
申请日期
2008.05.27
申请人
TIBOTEC PHARMACEUTICALS LTD
发明人
DE KOCK, HERMAN AUGUSTINUS;JONCKERS, TIM HUGO MARIA;LAST, STEFAAN JULIEN;BOONANTS, PAUL JOZEF GABRIEL MARIA;SURLERAUX, DOMINIQUE LOUIS NESTOR GHISLAIN;WIGERINCK, PIET TOM BERT PAUL