发明名称 Nitrogen-containing heterocyclic compound and use thereof
摘要 The present invention relates to a compound represented by the formula wherein ring A is a nitrogen-containing heterocycle optionally further having substituent(s), ring B is an aromatic ring optionally having substituent(s), ring C is a cyclic group optionally having substituent(s), R1 is a hydrogen atom, a hydrocarbon group optionally having substituent(s), an acyl group, a heterocyclic group optionally having substituent(s) or an amino group optionally having substituent(s), R2 is an optionally halogenated C1-6 alkyl group, m and n are each an integer of 0 to 5, m+n is an integer of 2 to 5, and <img id="CUSTOM-CHARACTER-00001" he="2.46mm" wi="6.35mm" file="US20090156572A1-20090618-P00001.TIF" img-content="character" img-format="tif"/> is a single bond or a double bond, or a salt thereof and the like. Since the compound has a superior tachykinin receptor antagonistic action, and is useful as an agent for the prophylaxis or treatment of various diseases such as lower urinary tract diseases, gastrointestinal diseases, central nervous system diseases and the like.
申请公布号 US2009156572(A1) 申请公布日期 2009.06.18
申请号 US20080314015 申请日期 2008.12.02
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 IKEURA YOSHINORI;SHIRAI JUNYA;SUGIYAMA HIDEYUKI;NISHIKIMI YUJI;KAMEI TAKU;SAKAUCHI NOBUKI
分类号 A61K31/397;A61K31/4545;A61K31/497;A61K31/4985;A61K31/5377;A61K31/541;C07D401/12;C07D401/14;C07D413/12;C07D417/14;C07D487/04 主分类号 A61K31/397
代理机构 代理人
主权项
地址